Eliprodil, aslo known as SL-82,0715; is a NMDA antagonist. NMDA receptors are a key component in mediating glutamate-induced excitotoxicity, and it is believed that NMDA antagonists would be neuroprotective after a stroke or other traumatic brain injury. Eliprodil protects pyramidal neurons in hippocampal slices from hypoxic/ischemic damage. Eliprodil stimulates CNS myelination, may be a new prospect for multiple sclerosis.
MedKoo Cat#: 127159
Name: Eliprodil hydrochloride
CAS#: 136634-88-3 (HCl)
Chemical Formula: C20H24Cl2FNO
Exact Mass: 383.1219
Molecular Weight: 384.32
Elemental Analysis: C, 62.51; H, 6.29; Cl, 18.45; F, 4.94; N, 3.64; O, 4.16
The following data is based on the product molecular weight 384.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
