Fructosazine | CAS#13185-73-4 | Antimicrobial

MedKoo Cat#: 145037 | Name: Fructosazine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fructosazine is a polyhydroxyalkylpyrazine reported to have antimicrobial activity against heat-resistant Escherichia coli AW 1.7. Fructosazine exerts antimicrobial action by permeabilizing the cell membrane, damaging membrane integrity, and fragmenting DNA. Fructosazine is also a flavoring agent in the food and tobacco industry.

Chemical Structure

Fructosazine

CAS#13185-73-4

Theoretical Analysis

MedKoo Cat#: 145037

Name: Fructosazine

CAS#: 13185-73-4

Chemical Formula: C12H20N2O8

Exact Mass: 320.1220

Molecular Weight: 320.30

Elemental Analysis: C, 45.00; H, 6.29; N, 8.75; O, 39.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Fructosazine;

IUPAC/Chemical Name

(1R,1'R,2S,2'S,3R,3'R)-1,1'-(pyrazine-2,5-diyl)bis(butane-1,2,3,4-tetraol)

InChi Key

NPWQIVOYGNUVEB-PAUJSFGCSA-N

InChi Code

1S/C12H20N2O8/c15-3-7(17)11(21)9(19)5-1-13-6(2-14-5)10(20)12(22)8(18)4-16/h1-2,7-12,15-22H,3-4H2/t7-,8-,9-,10-,11-,12-/m1/s1

SMILES Code

OC[C@@H](O)[C@@H](O)[C@H](O)C1=CN=C(C=N1)[C@@H](O)[C@H](O)[C@H](O)CO

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 320.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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Synthesis of water- compatible imprinted polymers of in situ produced fructosazine and 2,5-deoxyfructosazine. Talanta. 2012 Sep 15;99:816-23. doi: 10.1016/j.talanta.2012.07.035. Epub 2012 Jul 22. PMID: 22967628. 5: Zhao M, Araújo MM, Dal S, Sigrist S, Bergaentzlé M, Ramanitrahasimbola D, Andrianjara C, Marchioni E. Development and validation of a selective and effective pressurized liquid extraction followed by liquid chromatography-mass spectrometry method for the determination of fructosazine analogues in the ammonia treated extract of Eugenia jambolana Lamarck seeds. J Chromatogr A. 2016 Nov 18;1473:66-75. doi: 10.1016/j.chroma.2016.10.035. Epub 2016 Oct 13. PMID: 27771103. 6: Dhungel P, Hrynets Y, Betti M. Sous-Vide Nonenzymatic Browning of Glucosamine at Different Temperatures. J Agric Food Chem. 2018 May 2;66(17):4521-4530. doi: 10.1021/acs.jafc.8b01265. Epub 2018 Apr 23. PMID: 29658276. 7: Hrynets Y, Bhattacherjee A, Ndagijimana M, Hincapie Martinez DJ, Betti M. 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