MedKoo Cat#: 127145 | Name: Y08207

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Y08207 is a CBP inhibitor and degrader.

Chemical Structure

Y08207
Y08207
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 127145

Name: Y08207

CAS#: N/A

Chemical Formula: C22H19FN4O4

Exact Mass: 422.1390

Molecular Weight: 422.42

Elemental Analysis: C, 62.55; H, 4.53; F, 4.50; N, 13.26; O, 15.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Y-08207; Y 08207; Y08207
IUPAC/Chemical Name
3-acetyl-N-(2-fluoro-5-(hydroxymethyl)-3-(1-methyl-1H-pyrazol-4-yl)phenyl)-7-hydroxyindolizine-1-carboxamide
InChi Key
VLSSRXAUNKQKKE-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H19FN4O4/c1-12(29)19-8-17(20-7-15(30)3-4-27(19)20)22(31)25-18-6-13(11-28)5-16(21(18)23)14-9-24-26(2)10-14/h3-10,28,30H,11H2,1-2H3,(H,25,31)
SMILES Code
OC1=CC2=C(C(NC3=C(F)C(C4=CN(C)N=C4)=CC(CO)=C3)=O)C=C(C(C)=O)N2C=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 422.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Cai LY, Chen SJ, Xiao SH, Sun QJ, Ding CH, Zheng BN, Zhu XY, Liu SQ, Yang F, Yang YX, Zhou B, Luo C, Zhang X, Xie WF. Targeting p300/CBP Attenuates Hepatocellular Carcinoma Progression through Epigenetic Regulation of Metabolism. Cancer Res. 2021 Feb 15;81(4):860-872. doi: 10.1158/0008-5472.CAN-20-1323. Epub 2020 Dec 23. PMID: 33361394.