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MedKoo Cat#: 126783 | Name: SUN-1334

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SUN-1334H is a histamine H1 receptor antagonist potentially for the treatment of allergic conjunctivitis and allergic rhinitis

Chemical Structure

SUN-1334
SUN-1334
CAS#607737-00-8 (free base)

Theoretical Analysis

MedKoo Cat#: 126783

Name: SUN-1334

CAS#: 607737-00-8 (free base)

Chemical Formula: C23H26F2N2O3

Exact Mass: 416.1911

Molecular Weight: 416.47

Elemental Analysis: C, 66.33; H, 6.29; F, 9.12; N, 6.73; O, 11.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
607737-00-8 (free base) 607736-84-5 (HCl)
Synonym
SUN-1334; SUN1334; SUN 1334
IUPAC/Chemical Name
(E)-2-((4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)but-2-en-1-yl)oxy)acetic acid
InChi Key
PXQVDRLCSQHQTO-OWOJBTEDSA-N
InChi Code
InChI=1S/C23H26F2N2O3/c24-20-7-3-18(4-8-20)23(19-5-9-21(25)10-6-19)27-14-12-26(13-15-27)11-1-2-16-30-17-22(28)29/h1-10,23H,11-17H2,(H,28,29)/b2-1+
SMILES Code
OC(=O)COC\C=C\CN1CCN(CC1)C(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 416.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Mandhane SN, Shah JH, Bahekar PC, Mehetre SV, Pawar CA, Bagad AS, Chidrewar GU, Rao CT, Rajamannar T. Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H. Int Arch Allergy Immunol. 2010;151(1):56-69. doi: 10.1159/000232571. PubMed PMID: 19672097. 2: Mandhane SN, Ayer UB, Midha AS, Rao CT, Rajamannar T. Preclinical efficacy and safety pharmacology of SUN-1334H, a potent orally active antihistamine agent. Drugs R D. 2008;9(2):93-112. PubMed PMID: 18298128.