YFJ-36 is an antibiotics. YFJ-36 exhibited superior and broad-spectrum in vitro antibacterial activity, especially against A. baumannii and K. pneumoniae, compared with cefiderocol. Potent in vivo efficacy was observed in a murine systemic infection model. Furthermore, the physicochemical stability of YFJ-36 in fluid medium at pH 6−8 was enhanced. YFJ-36 also reduced potential the risk of allergy owing to the quaternary ammonium linker.
MedKoo Cat#: 126756
Name: YFJ-36
CAS#: N/A
Chemical Formula: C30H31ClF2N6O10S3
Exact Mass: 804.0920
Molecular Weight: 805.24
Elemental Analysis: C, 44.75; H, 3.88; Cl, 4.40; F, 4.72; N, 10.44; O, 19.87; S, 11.94
The following data is based on the product molecular weight 805.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
