Tandospirone, also known as SM-3997, is a 5-HT1A receptor partial agonist that displays selectivity over 5-HT2, 5-HT1C, α1, α2, D1 and D2 receptors. It is inactive at 5-HT uptake sites, 5-HT1B, β-adrenergic, muscarinic and benzodiazepine receptors. It displays anxiolytic activity.
MedKoo Cat#: 126685
Name: Tandospirone free base
CAS#: 87760-53-0 (free base)
Chemical Formula: C21H29N5O2
Exact Mass: 383.2321
Molecular Weight: 383.50
Elemental Analysis: C, 65.77; H, 7.62; N, 18.26; O, 8.34
The following data is based on the product molecular weight 383.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
