MedKoo Cat#: 126653 | Name: 10-keto Naltrexone
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

10-keto Naltrexone is an antagonist of μ-, κ-, and δ-opioid receptors (Kis = 31.1, 102, and 281 nM, respectively, for the guinea pig receptors).

Chemical Structure

10-keto Naltrexone
10-keto Naltrexone
CAS#96445-14-6

Theoretical Analysis

MedKoo Cat#: 126653

Name: 10-keto Naltrexone

CAS#: 96445-14-6

Chemical Formula: C20H21NO5

Exact Mass: 355.1420

Molecular Weight: 355.39

Elemental Analysis: C, 67.59; H, 5.96; N, 3.94; O, 22.51

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 750.00 2 Weeks
10mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
10-oxo Naltrexone; 10-keto Naltrexone; 10 keto Naltrexone; 10keto Naltrexone
IUPAC/Chemical Name
(4S,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,13(7aH)-dione
InChi Key
MLHMRULRADVYER-FUMNGEBKSA-N
InChi Code
InChI=1S/C20H21NO5/c22-12-4-3-11-14-16(12)26-18-13(23)5-6-20(25)17(15(11)24)21(9-10-1-2-10)8-7-19(14,18)20/h3-4,10,17-18,22,25H,1-2,5-9H2/t17-,18+,19+,20-/m1/s1
SMILES Code
O[C@@]([C@@]12[H])(CCC3=O)[C@@]([C@@]3([H])OC4=C5O)(CCN2CC6CC6)C4=C(C=C5)C1=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 355.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL