Tortuosamine | CAS#35722-04-4 | Alkaloid

MedKoo Cat#: 145105 | Name: Tortuosamine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tortuosamine is one of the alkaloids identified in Sceletium tortuosum. Tortuosamine is highlighted in studies for its diverse biological activities, including neuroprotection, anti-HIV properties, and enhancement of cognitive function.

Chemical Structure

Tortuosamine

CAS#35722-04-4

Theoretical Analysis

MedKoo Cat#: 145105

Name: Tortuosamine

CAS#: 35722-04-4

Chemical Formula: C20H26N2O2

Exact Mass: 326.1994

Molecular Weight: 326.44

Elemental Analysis: C, 73.59; H, 8.03; N, 8.58; O, 9.80

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Tortuosamine;

IUPAC/Chemical Name

(R)-2-(6-(3,4-dimethoxyphenyl)-5,6,7,8-tetrahydroquinolin-6-yl)-N-methylethan-1-amine

InChi Key

QFRVOGLOHJOHAY-FQEVSTJZSA-N

InChi Code

1S/C20H26N2O2/c1-21-12-10-20(9-8-17-15(14-20)5-4-11-22-17)16-6-7-18(23-2)19(13-16)24-3/h4-7,11,13,21H,8-10,12,14H2,1-3H3/t20-/m0/s1

SMILES Code

CNCC[C@]1(CCC2=NC=CC=C2C1)C3=CC(OC)=C(OC)C=C3

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 326.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Olatunji TL, Siebert F, Adetunji AE, Harvey BH, Gericke J, Hamman JH, Van der Kooy F. Sceletium tortuosum: A review on its phytochemistry, pharmacokinetics, biological and clinical activities. J Ethnopharmacol. 2021 Nov 15;280:114476. doi: 10.1016/j.jep.2021.114476. Epub 2021 Jul 30. Erratum in: J Ethnopharmacol. 2022 Apr 6;287:114711. doi: 10.1016/j.jep.2021.114711. PMID: 34333104. 2: Olatunji TL, Siebert F, Adetunji AE, Harvey BH, Gericke J, Hamman JH, Van der Kooy F. Sceletium tortuosum: A review on its phytochemistry, pharmacokinetics, biological, pre-clinical and clinical activities. J Ethnopharmacol. 2022 Apr 6;287:114711. doi: 10.1016/j.jep.2021.114711. Epub 2021 Nov 8. Erratum for: J Ethnopharmacol. 2021 Nov 15;280:114476. doi: 10.1016/j.jep.2021.114476. PMID: 34758918. 3: Elgoud Said AA, Afifi AH, Ali TFS, Samy MN, Abdelmohsen UR, Fouad MA, Attia EZ. NS3/4A helicase inhibitory alkaloids from Aptenia cordifolia as HCV target. RSC Adv. 2021 Oct 6;11(52):32740-32749. doi: 10.1039/d1ra06139a. PMID: 35493564; PMCID: PMC9042107. 4: Manyawi M, Mozirandi WY, Tagwireyi D, Mukanganyama S. Fractionation and Antibacterial Evaluation of the Surface Compounds from the Leaves of Combretum zeyheri on Selected Pathogenic Bacteria. ScientificWorldJournal. 2023 Jul 21;2023:2322068. doi: 10.1155/2023/2322068. PMID: 37520845; PMCID: PMC10382245.