MedKoo Cat#: 126615 | Name: Stearoylcarnitine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Stearoylcarnitine, also known as acylcarnitine C18:0, is a fatty ester lipid molecule. It is found in significantly greater amounts of patients with carnitine palmitoyltransferase (CPT) II deficiency when compared to controls. Stearoylcarnitine is also found to be associated with celiac disease, another inborn error of metabolism. The carnitine palmitoyltransferase (CPT; EC 2.3.1.21) enzyme system, in conjunction with acyl-CoA synthetase and carnitine/acylcarnitine translocase, provides the mechanism whereby long-chain fatty acids are transferred from the cytosol to the mitochondrial matrix to undergo beta-oxidation. Stearoylcarnitine is considered to be practically insoluble in water and acidic.

Chemical Structure

Stearoylcarnitine
Stearoylcarnitine
CAS#25597-09-5

Theoretical Analysis

MedKoo Cat#: 126615

Name: Stearoylcarnitine

CAS#: 25597-09-5

Chemical Formula: C25H49NO4

Exact Mass: 427.3662

Molecular Weight: 427.67

Elemental Analysis: C, 70.21; H, 11.55; N, 3.28; O, 14.96

Price and Availability

Size Price Availability Quantity
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
200mg USD 2,050.00 2 Weeks
1g USD 4,450.00 2 Weeks
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Related CAS #
No Data
Synonym
stearoylcarnitine; 25597-09-5; (-)-Stearoylcarnitine; O-stearoyl-L-carnitine; O-octadecanoyl-L-carnitine; acylcarnitine C18:0;
IUPAC/Chemical Name
(R)-3-(stearoyloxy)-4-(trimethylammonio)butanoate
InChi Key
FNPHNLNTJNMAEE-HSZRJFAPSA-N
InChi Code
InChI=1S/C25H49NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-25(29)30-23(21-24(27)28)22-26(2,3)4/h23H,5-22H2,1-4H3/t23-/m1/s1
SMILES Code
CCCCCCCCCCCCCCCCCC(O[C@H](CC([O-])=O)C[N+](C)(C)C)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 427.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kerner J, Minkler PE, Lesnefsky EJ, Hoppel CL. Fatty acid chain-elongation in perfused rat heart: synthesis of stearoylcarnitine from perfused palmitate. FEBS Lett. 2007 Sep 18;581(23):4491-4. doi: 10.1016/j.febslet.2007.08.026. Epub 2007 Aug 22. PMID: 17761175; PMCID: PMC2743553. 2: Kamlekar RK, Swamy MJ. Studies on the critical micellar concentration and phase transitions of stearoylcarnitine. Biosci Rep. 2006 Dec;26(6):387-98. doi: 10.1007/s10540-006-9027-7. PMID: 17029002.