Zaltidine hydrochloride | H2-receptor antagonist | CAS#90274-23-0

MedKoo Cat#: 126590 | Name: Zaltidine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Zaltidine (CP-57,361) is a guanidinothiazolylimidazole compound which is a highly specific H2-receptor antagonist.

Chemical Structure

Zaltidine hydrochloride

CAS#90274-23-0 (HCl)

Theoretical Analysis

MedKoo Cat#: 126590

Name: Zaltidine hydrochloride

CAS#: 90274-23-0 (HCl)

Chemical Formula: C8H12Cl2N6S

Exact Mass: 294.0221

Molecular Weight: 295.19

Elemental Analysis: C, 32.55; H, 4.10; Cl, 24.02; N, 28.47; S, 10.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

85604-00-8 (free base) 90274-23-0 (HCl)

Synonym

ZALTIDINE HCL; ZALTIDINE HYDROCHLORIDE; CP-57,361-01; CP-57361-01;

IUPAC/Chemical Name

1-(4-(2-methyl-1H-imidazol-5-yl)thiazol-2-yl)guanidine dihydrochloride

InChi Key

BJEGCKZYQRBQMG-UHFFFAOYSA-N

InChi Code

InChI=1S/C8H10N6S.2ClH/c1-4-11-2-5(12-4)6-3-15-8(13-6)14-7(9)10;;/h2-3H,1H3,(H,11,12)(H4,9,10,13,14);2*1H

SMILES Code

Cl.Cl.CC1=NC=C(N1)C2=CSC(NC(N)=N)=N2

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 295.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Farup PG. Zaltidine: an effective but hepatotoxic H2-receptor antagonist. Scand J Gastroenterol. 1988 Aug;23(6):655-8. PubMed PMID: 2902681. 2: Laferla G, Buchanan N, Hearns J, Crean GP, McColl KE, Clucas AT. The antisecretory effects of zaltidine, a novel long-acting H2-receptor antagonist, in healthy volunteers and in subjects with a past history of duodenal ulcer. Br J Clin Pharmacol. 1986 Oct;22(4):395-9. PubMed PMID: 2876724; PubMed Central PMCID: PMC1401146. 3: Hunter RP, Canning PC, Hassfurther R. Plasma analysis and pharmacokinetics of zaltidine, an H2-antagonist, in cattle after intravenous, intramuscular, subcutaneous, and oral administration. J Vet Pharmacol Ther. 1996 Aug;19(4):326-8. PubMed PMID: 8866466.