OXA-06 is a potent ROCK inhibitor(IC50 = 10 nM). OXA-06 suppresses pMYPT1 and pCofilin levels in non-small cell lung carcinoma (NSCLC) cell lines. OXA-06 also inhibits anchorage-independent growth of NSCLC cell lines in vitro.
MedKoo Cat#: 556365
Name: OXA-06 HCl
CAS#: 1825455-91-1 (HCl)
Chemical Formula: C21H20Cl2FN3
Exact Mass: 0.0000
Molecular Weight: 404.31
Elemental Analysis: C, 62.39; H, 4.99; Cl, 17.54; F, 4.70; N, 10.39
The following data is based on the product molecular weight 404.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
