Yoda 2 is a selective Piezo1 channel activator (EC50 values are 150 nM and 1.14 μM in mPiezo1 and HUVEC cells respectively). Increases Ca2+ signaling 2.8 fold in hPIEZO-TREx and 1.2 fold in mPIEZO1-TREx, compared to Yoda 1
MedKoo Cat#: 126392
Name: Yoda 2
CAS#: N/A
Chemical Formula: C16H9Cl2KN2O2S2
Exact Mass: 433.9120
Molecular Weight: 435.38
Elemental Analysis: C, 44.14; H, 2.08; Cl, 16.28; K, 8.98; N, 6.43; O, 7.35; S, 14.73
The following data is based on the product molecular weight 435.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
