MedKoo Cat#: 126353 | Name: HD57

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HD57 is an AR/GR dual inhibitor.

Chemical Structure

HD57
HD57
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 126353

Name: HD57

CAS#: N/A

Chemical Formula: C20H22N2O3S

Exact Mass: 370.1351

Molecular Weight: 370.47

Elemental Analysis: C, 64.84; H, 5.99; N, 7.56; O, 12.96; S, 8.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
HD57; HD-57; HD 57
IUPAC/Chemical Name
N-(3-ethylphenyl)-3-oxo-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline-9-sulfonamide
InChi Key
HODLFVVDCRYGDU-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H22N2O3S/c1-2-14-5-3-7-17(11-14)21-26(24,25)18-12-15-6-4-10-22-19(23)9-8-16(13-18)20(15)22/h3,5,7,11-13,21H,2,4,6,8-10H2,1H3
SMILES Code
O=C1N(CCCC2=CC(S(NC3=CC=CC(CC)=C3)(=O)=O)=C4)C2=C4CC1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 370.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Chai X, Hu XP, Wang XY, Wang HT, Pang JP, Zhou WF, Liao JN, Shan LH, Xu XH, Xu L, Xia HG, Hou TJ, Li D. Computationally guided discovery of novel non-steroidal AR-GR dual antagonists demonstrating potency against antiandrogen resistance. Acta Pharmacol Sin. 2023 Jul;44(7):1500-1518. doi: 10.1038/s41401-022-01038-7. Epub 2023 Jan 13. PMID: 36639570; PMCID: PMC10310723.