MedKoo Cat#: 556026 | Name: FTO-IN-7
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

FTO-IN-7 is a FTO inhibitor for treatment of leukemia. This compound was first reported in patent WO 2018157842. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

FTO-IN-7
FTO-IN-7
CAS#2243736-37-8

Theoretical Analysis

MedKoo Cat#: 556026

Name: FTO-IN-7

CAS#: 2243736-37-8

Chemical Formula: C18H15Cl2N3O2

Exact Mass: 375.0541

Molecular Weight: 376.24

Elemental Analysis: C, 57.46; H, 4.02; Cl, 18.84; N, 11.17; O, 8.50

Price and Availability

Size Price Availability Quantity
100mg USD 1,650.00 2 Weeks
200mg USD 2,650.00 2 Weeks
500mg USD 3,650.00 2 Weeks
1g USD 4,650.00 2 Weeks
2g USD 6,450.00 2 Weeks
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Related CAS #
No Data
Synonym
FTO-IN-7; FTO IN-7; FTO-IN 7; FTO IN 7
IUPAC/Chemical Name
2-[[2,6-Dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]benzoic acid
InChi Key
MCENODSHXUWMEL-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H15Cl2N3O2/c1-9-16(10(2)23-22-9)11-7-13(19)17(14(20)8-11)21-15-6-4-3-5-12(15)18(24)25/h3-8,21H,1-2H3,(H,22,23)(H,24,25)
SMILES Code
O=C(O)C1=CC=CC=C1NC2=C(Cl)C=C(C3=C(C)NN=C3C)C=C2Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 376.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Liu Z, Duan Z, Zhang D, Xiao P, Zhang T, Xu H, Wang CH, Rao GW, Gan J, Huang Y, Yang CG, Dong Z. Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors. J Med Chem. 2022 Aug 11;65(15):10638-10654. doi: 10.1021/acs.jmedchem.2c00848. Epub 2022 Jul 6. PMID: 35793358.