PAG (phenyl amino glutarimide) 4'-piperazine is a functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand with a terminal piperazine for onward chemistry to generate Protein Degraders with rigid linkers.
MedKoo Cat#: 126340
Name: PAG 4'-piperazine
CAS#: 2922286-32-4
Chemical Formula: C15H22Cl2N4O2
Exact Mass: 360.1120
Molecular Weight: 361.27
Elemental Analysis: C, 49.87; H, 6.14; Cl, 19.63; N, 15.51; O, 8.86
The following data is based on the product molecular weight 361.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
