Synonym
Lysinenorleucine; Lys-nle;
IUPAC/Chemical Name
(2S,2'S)-6,6'-azanediylbis(2-aminohexanoic acid)
InChi Key
HYLBTMZBXLEVCL-UWVGGRQHSA-N
InChi Code
InChI=1S/C12H25N3O4/c13-9(11(16)17)5-1-3-7-15-8-4-2-6-10(14)12(18)19/h9-10,15H,1-8,13-14H2,(H,16,17)(H,18,19)/t9-,10-/m0/s1
SMILES Code
N[C@@H](CCCCNCCCC[C@H](N)C(O)=O)C(O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Biological target:
Lysinenorleucine is a Lysine and hydroxylysine derivatives for treatment of malignant and benign tumors.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
275.35
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
Formulation protocol:
TBD
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3: Nielsen CJ, Bentley JP, Marshall FJ. Age-related changes in reducible crosslinks of human dental pulp collagen. Arch Oral Biol. 1983;28(8):759-64. PubMed PMID: 6579908.
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5: Levene CI, Heale G, Robins SP. Collagen cross-link synthesis in cultured vascular endothelium. Br J Exp Pathol. 1989 Dec;70(6):621-6. PubMed PMID: 2605112; PubMed Central PMCID: PMC2040723.
6: Richmond VL. The microfibrillar components of porcine lung elastic fiber. Biochim Biophys Acta. 1981 Jul 28;669(2):193-205. PubMed PMID: 7197163.
7: Konieczny L, Piekarska B, Rybarska J, Stopa B, Krzykwa B, Noworolski J, Pawlicki R, Roterman I. Bis azo dye liquid crystalline micelles as possible drug carriers in immunotargeting technique. J Physiol Pharmacol. 1994 Sep;45(3):441-54. PubMed PMID: 7841456.
