MedKoo Cat#: 555994 | Name: (S,S,S)-AHPC HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(S,S,S)-AHPC (HCl salt) is a ligand used as a negative control for (S,R,S)-AHPC in the recruitment of the von Hippel–Lindau (VHL) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.

Chemical Structure

(S,S,S)-AHPC HCl
(S,S,S)-AHPC HCl
CAS#2115897-23-7 (HCl)

Theoretical Analysis

MedKoo Cat#: 555994

Name: (S,S,S)-AHPC HCl

CAS#: 2115897-23-7 (HCl)

Chemical Formula: C22H31ClN4O3S

Exact Mass:

Molecular Weight: 467.02

Elemental Analysis: C, 56.58; H, 6.69; Cl, 7.59; N, 12.00; O, 10.28; S, 6.86

Price and Availability

Size Price Availability Quantity
10mg USD 650.00 2 Weeks
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Related CAS #
1797406-78-0 (free base) 2115897-23-7 (HCl)
Synonym
(S,S,S)-AHPC HCl; (S,S,S)-AHPC hydrochloride; (S,S,S)-AHPC; E3 Ligase ligand negative control epimer; Ligand for PROTAC® research; VH032 negative control;
IUPAC/Chemical Name
(2S,4S)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
InChi Key
JYRTWGCWUBURGU-ITJMAPPJSA-N
InChi Code
InChI=1S/C22H30N4O3S.ClH/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16(27)11-26(17)21(29)19(23)22(2,3)4;/h5-8,12,16-17,19,27H,9-11,23H2,1-4H3,(H,24,28);1H/t16-,17-,19+;/m0./s1
SMILES Code
O=C([C@H]1N(C([C@@H](N)C(C)(C)C)=O)C[C@@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 467.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL