Ropitoin HCl | CAS#56079-80-2 | diphenylhydantoin derivative

MedKoo Cat#: 126158 | Name: Ropitoin HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ropitoin (TR2985) is a diphenylhydantoin derivative.

Chemical Structure

Ropitoin HCl

CAS#56079-80-2 (HCl)

Theoretical Analysis

MedKoo Cat#: 126158

Name: Ropitoin HCl

CAS#: 56079-80-2 (HCl)

Chemical Formula: C30H34ClN3O3

Exact Mass: 519.2289

Molecular Weight: 520.07

Elemental Analysis: C, 69.28; H, 6.59; Cl, 6.82; N, 8.08; O, 9.23

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

56079-80-2 (HCl) 56079-81-3 (free base)

Synonym

Ropitoin; TR2985; ROPITOIN HYDROCHLORIDE; Ropitoin HCl; Ropitoin hydrochloride

IUPAC/Chemical Name

5-(4-methoxyphenyl)-5-phenyl-3-(3-(4-phenylpiperidin-1-yl)propyl)imidazolidine-2,4-dione hydrochloride

InChi Key

IYHQTOOPUMZKRX-UHFFFAOYSA-N

InChi Code

InChI=1S/C30H33N3O3.ClH/c1-36-27-15-13-26(14-16-27)30(25-11-6-3-7-12-25)28(34)33(29(35)31-30)20-8-19-32-21-17-24(18-22-32)23-9-4-2-5-10-23;/h2-7,9-16,24H,8,17-22H2,1H3,(H,31,35);1H

SMILES Code

Cl.COC1=CC=C(C=C1)C2(NC(=O)N(CCCN3CCC(CC3)C4=CC=CC=C4)C2=O)C5=CC=CC=C5

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 520.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Elizalde A, Sanchéz-Chapula J. Effects of the novel antiarrhythmic compound TR 2985 (ropitoin) on action potentials of different mammalian cardiac tissues. Naunyn Schmiedebergs Arch Pharmacol. 1988 Mar;337(3):316-22. PubMed PMID: 3393234. 2: Valenzuela C, Sanchez-Chapula J. Electrophysiologic interactions between mexiletine-quinidine and mexiletine-ropitoin in guinea pig papillary muscle. J Cardiovasc Pharmacol. 1989 Nov;14(5):783-9. PubMed PMID: 2481194. 3: Hong E, Gonzalez-Jasso E, Peon J. Antiarrhythmic activity of ropitoin in rats subjected to coronary artery ligation. Proc West Pharmacol Soc. 1986;29:15-7. PubMed PMID: 3763601.