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MedKoo Cat#: 126155 | Name: Tazadolene

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tazadolene is a non-opioid analgesic with antidepressant properties.

Chemical Structure

Tazadolene
Tazadolene
CAS#87936-75-2 (free base)

Theoretical Analysis

MedKoo Cat#: 126155

Name: Tazadolene

CAS#: 87936-75-2 (free base)

Chemical Formula: C16H21N

Exact Mass: 227.1674

Molecular Weight: 227.35

Elemental Analysis: C, 84.53; H, 9.31; N, 6.16

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
87936-82-1 (succinate) 87936-75-2 (free base)
Synonym
TAZADOLENE; Tazadolene [INN]; 87936-75-2; Tazadolene, (+)- ; Tazadolene, (-)-
IUPAC/Chemical Name
(E)-1-(2-benzylidenecyclohexyl)azetidine
InChi Key
DOWWDQZIFWLREB-FYWRMAATSA-N
InChi Code
InChI=1S/C16H21N/c1-2-7-14(8-3-1)13-15-9-4-5-10-16(15)17-11-6-12-17/h1-3,7-8,13,16H,4-6,9-12H2/b15-13+
SMILES Code
N1(C2CCCC/C2=C\C3=CC=CC=C3)CCC1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 227.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Vonvoigtlander PF, Lewis RA. Evidence for the combined involvement of serotonergic and alpha 2 adrenergic mechanisms in the analgesic activity of tazadolene succinate. Drug Des Deliv. 1987 Dec;2(2):129-33. PMID: 2855569. 2. VonVoigtlander PF, Chidester CG, Kane MP, Szmuszkovicz J. Tazadolene succinate: a structurally novel non-opioid analgesic with antidepressant properties. Drug Des Deliv. 1986 Nov;1(2):103-8. PMID: 3509323.