MedKoo Cat#: 126132 | Name: XST-14
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

XST-14 is a specific inhibitor of ULK1 to suppress HCC progression.

Chemical Structure

XST-14
XST-14
CAS#2607143-50-8

Theoretical Analysis

MedKoo Cat#: 126132

Name: XST-14

CAS#: 2607143-50-8

Chemical Formula: C16H21NO4

Exact Mass: 291.1471

Molecular Weight: 291.35

Elemental Analysis: C, 65.96; H, 7.27; N, 4.81; O, 21.97

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
25mg USD 950.00 2 Weeks
100mg USD 1,650.00 2 Weeks
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Related CAS #
No Data
Synonym
XST-14; XST 14; XST14
IUPAC/Chemical Name
methyl 4,6-diisopropoxy-1H-indole-2-carboxylate
InChi Key
ZNFMBFABCSHXPM-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H21NO4/c1-9(2)20-11-6-13-12(15(7-11)21-10(3)4)8-14(17-13)16(18)19-5/h6-10,17H,1-5H3
SMILES Code
CC(C)OC1=CC2=C(C=C(N2)C(=O)OC)C(=C1)OC(C)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 291.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gao Y, Zhou Z, Zhang T, Xue S, Li K, Jiang J. Structure-Based Virtual Screening towards the Discovery of Novel ULK1 Inhibitors with Anti-HCC Activities. Molecules. 2022 Apr 19;27(9):2627. doi: 10.3390/molecules27092627. PMID: 35565977; PMCID: PMC9102329. 2: Xue ST, Li K, Gao Y, Zhao LY, Gao Y, Yi H, Jiang JD, Li ZR. The role of the key autophagy kinase ULK1 in hepatocellular carcinoma and its validation as a treatment target. Autophagy. 2020 Oct;16(10):1823-1837. doi: 10.1080/15548627.2019.1709762. Epub 2020 Jan 27. PMID: 31986961; PMCID: PMC8386607.