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MedKoo Cat#: 125945 | Name: PF-03049423 free base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PF-03049423 (Compound PF-5) is a potent and highly selective phosphodiesterase-5A inhibitor with an IC50of about 0.2 nM for rat and human platelet enzyme

Chemical Structure

PF-03049423 free base
CAS#954138-07-9

Theoretical Analysis

MedKoo Cat#: 125945

Name: PF-03049423 free base

CAS#: 954138-07-9

Chemical Formula: C24H32N6O4

Exact Mass: 468.2485

Molecular Weight: 468.56

Elemental Analysis: C, 61.52; H, 6.88; N, 17.94; O, 13.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
PF-03049423 free base; PF-03049423; PF03049423; PF 03049423; PF-3049423; PF3049423; PF 3049423
IUPAC/Chemical Name
3-(4-(2-hydroxyethyl)piperazin-1-yl)-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one
InChi Key
MNLNAGRCHNMKKJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H32N6O4/c1-3-13-34-14-11-30-21-15-19(18-4-5-22(33-2)26-16-18)25-17-20(21)27-23(24(30)32)29-8-6-28(7-9-29)10-12-31/h4-5,15-17,31H,3,6-14H2,1-2H3
SMILES Code
CCCOCCN1C(=O)C(=NC2=C1C=C(N=C2)C3=CC=C(OC)N=C3)N4CCN(CCO)CC4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 468.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL