Tomeglovir, also known as BAY-38-4766, is a non-nucleoside antiviral. Tomeglovir protects against cytomegalovirus (CMV) disease and mortality in immunocompromised guinea pigs. BAY 38-4766-resistant HCMV and MCMV strains are not cross-resistant to the nucleoside analogues ganciclovir and cidofovir or the pyrophosphate analogue foscarnet, indicating a different mode of action. Tomeglovir is highly specific for the viral as opposed to cellular functions, since UL89 is related to a bacteriophage terminase and no human equivalent exists.
MedKoo Cat#: 526470
Name: Tomeglovir
CAS#: 233254-24-5
Chemical Formula: C23H27N3O4S
Exact Mass: 441.1722
Molecular Weight: 441.55
Elemental Analysis: C, 62.56; H, 6.16; N, 9.52; O, 14.49; S, 7.26
The following data is based on the product molecular weight 441.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
