N6F11 is an inducer of ferroptosis.1 It increases the thermal stability of the ubiquitin ligase TRIM25 in a cellular thermal shift assay (CETSA) using PANC-1 pancreatic cancer cells when used at a concentration of 10 µM and enhances TRIM25-dependent ubiquitination of glutathione peroxidase 4 (GPX4) in a cell-free assay at 0.1 and 1 µM.
MedKoo Cat#: 125916
Name: N6F11
CAS#: 851398-76-0
Chemical Formula: C13H10Cl2N2OS
Exact Mass: 311.9891
Molecular Weight: 313.20
Elemental Analysis: C, 49.85; H, 3.22; Cl, 22.64; N, 8.94; O, 5.11; S, 10.24
The following data is based on the product molecular weight 313.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
