MNI-420 I-123 | CAS#1628318-66-0 | single photon emission computed tomography | radiotracer

MedKoo Cat#: 125365 | Name: MNI-420 I-123

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MNI-420 I-123 is a novel single photon emission computed tomography radiotracer for imaging of adenosine 2A receptors

Chemical Structure

MNI-420 I-123

CAS#1628318-66-0

Theoretical Analysis

MedKoo Cat#: 125365

Name: MNI-420 I-123

CAS#: 1628318-66-0

Chemical Formula: C22H21F123IN9O

Exact Mass: 569.0900

Molecular Weight: 569.38

Elemental Analysis: C, 46.41; H, 3.72; F, 3.34; I, 21.59; N, 22.14; O, 2.81

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

MNI-420 I-123; (123I)Mni 420; 7F72N88C2C; UNII-7F72N88C2C; 1628318-66-0

IUPAC/Chemical Name

7-(2-(4-(2-fluoro-4-(iodo-123I)phenyl)piperazin-1-yl)ethyl)-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine

InChi Key

JVFOCNGXDZHLFX-JNYMONNXSA-N

InChi Code

InChI=1S/C22H21FIN9O/c23-16-12-14(24)3-4-17(16)31-8-5-30(6-9-31)7-10-32-20-15(13-26-32)21-27-19(18-2-1-11-34-18)29-33(21)22(25)28-20/h1-4,11-13H,5-10H2,(H2,25,28)/i24-4

SMILES Code

NC1=NC2=C(C=NN2CCN3CCN(CC3)C4=CC=C([123I])C=C4F)C5=NC(=NN15)C6=CC=CO6

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 569.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tavares AA, Batis JC, Papin C, Jennings D, Alagille D, Russell DS, Vala C, Lee H, Baldwin RM, Zubal IG, Marek KL, Seibyl JP, Barret O, Tamagnan GD. Kinetic modeling, test-retest, and dosimetry of 123I-MNI-420 in humans. J Nucl Med. 2013 Oct;54(10):1760-7. doi: 10.2967/jnumed.113.119933. Epub 2013 Aug 22. PMID: 23970369. 2: Tavares AA, Batis J, Barret O, Alagille D, Vala C, Kudej G, Koren A, Cosgrove KP, Nice K, Kordower JH, Seibyl J, Tamagnan GD. In vivo evaluation of [(123)I]MNI-420: a novel single photon emission computed tomography radiotracer for imaging of adenosine 2A receptors in brain. Nucl Med Biol. 2013 Apr;40(3):403-9. doi: 10.1016/j.nucmedbio.2012.12.005. Epub 2013 Jan 16. PMID: 23332393.