JNJ-37822681 2HCl | D(2) antagonist | CAS#2108806-02-4

MedKoo Cat#: 125342 | Name: JNJ-37822681 2HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

JNJ-37822681 is a novel, potent, specific, centrally active, and fast-dissociating D(2) antagonist with optimal brain disposition. JNJ-37822681 is the first compound that allows the evaluation of the potential value of fast D(2) antagonism for the treatment of schizophrenia and bipolar disorder.

Chemical Structure

JNJ-37822681 2HCl

CAS#2108806-02-4 (2HCl)

Theoretical Analysis

MedKoo Cat#: 125342

Name: JNJ-37822681 2HCl

CAS#: 2108806-02-4 (2HCl)

Chemical Formula: C17H19Cl2F5N4

Exact Mass: 444.0900

Molecular Weight: 445.26

Elemental Analysis: C, 45.86; H, 4.30; Cl, 15.92; F, 21.33; N, 12.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

935776-74-2 (free base) 2108806-02-4 (2HCl)

Synonym

JNJ-37822681 dihydrochloride; 2108806-02-4; JNJ-37822681 (dihydrochloride); Y3XCP46PA8; JNJ37822681dihydrochloride

IUPAC/Chemical Name

N-(1-(3,4-difluorobenzyl)piperidin-4-yl)-6-(trifluoromethyl)pyridazin-3-amine dihydrochloride

InChi Key

UOLHGUUKFNZTNS-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H17F5N4.2ClH/c18-13-2-1-11(9-14(13)19)10-26-7-5-12(6-8-26)23-16-4-3-15(24-25-16)17(20,21)22;;/h1-4,9,12H,5-8,10H2,(H,23,25);2*1H

SMILES Code

FC1=CC=C(C=C1F)CN2CCC(NC3=NN=C(C(F)(F)F)C=C3)CC2.Cl.Cl

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 445.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.