KI 3315 | CAS#138772-58-4

MedKoo Cat#: 535707 | Name: KI 3315

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KI 3315 is a potassium channel opener; a derivative of KRN 2391.

Chemical Structure

KI 3315

CAS#138772-58-4

Theoretical Analysis

MedKoo Cat#: 535707

Name: KI 3315

CAS#: 138772-58-4

Chemical Formula: C9H10N4O

Exact Mass: 190.0855

Molecular Weight: 190.21

Elemental Analysis: C, 56.83; H, 5.30; N, 29.46; O, 8.41

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

KI 3315; KI-3315; KI3315

IUPAC/Chemical Name

3-Pyridinecarboximidamide, N-cyano-N'-(2-hydroxyethyl)-

InChi Key

XAKMGGUQIOVNKY-UHFFFAOYSA-N

InChi Code

InChI=1S/C9H10N4O/c10-7-13-9(12-4-5-14)8-2-1-3-11-6-8/h1-3,6,14H,4-5H2,(H,12,13)

SMILES Code

OCC/N=C(C1=CC=CN=C1)/NC#N

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 190.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tanaka Y, Okada Y, Yokoyama T, Nakajima T, Izawa T, Fukushima H, Ogawa N. In vitro and in vivo K channel-opening effects of Ki3315, a metabolite of the novel vasodilator KRN2391. Arch Int Pharmacodyn Ther. 1993 Nov-Dec;326:62-71. PMID: 8185414. 2: Ishibashi T, Hamaguchi M, Imai S. Vasodilating properties of KRN2391: structural basis of a new pyridine-type potassium channel opener with a nitrate moiety. Naunyn Schmiedebergs Arch Pharmacol. 1992 Jul;346(1):94-101. doi: 10.1007/BF00167577. PMID: 1357559. 3: Yokoyama T, Okada Y, Jinno Y, Izumi H, Izawa T, Ogawa N. Comparative analysis of vasodilating mechanisms of Ki1769, Ki3315 and KRN2391, pyridinecarboximidamide derivatives, in porcine isolated coronary artery. Gen Pharmacol. 1994 Sep;25(5):941-5. doi: 10.1016/0306-3623(94)90100-7. PMID: 7835641. 4: Okada Y, Yokoyama T, Jinno Y, Kashiwabara T, Izawa T, Fukushima H, Ogawa N. Vasorelaxant action of Ki1769, a new pyridinecarboximidamide, in isolated porcine coronary artery. Eur J Pharmacol. 1993 Sep 14;241(2-3):177-81. doi: 10.1016/0014-2999(93)90200-2. PMID: 8243553. 5: Okada Y, Yanagisawa T, Taira N. An analysis of the nitrate-like and K channel opening actions of KRN2391 in canine coronary arterial smooth muscle. Br J Pharmacol. 1991 Dec;104(4):829-38. doi: 10.1111/j.1476-5381.1991.tb12514.x. PMID: 1810597; PMCID: PMC1908846. 6: Iwatsuki K, Horiuchi A, Ren LM, Chiba S. Effects of KRN2391, a novel vasodilator, on pancreatic exocrine secretion in anesthetized dogs. Eur J Pharmacol. 1993 Nov 2;249(1):19-24. doi: 10.1016/0014-2999(93)90657-4. PMID: 8282016.