Quinacillin | semisynthetic penicillase-resistant penicillin | CAS#985-32-0

MedKoo Cat#: 125303 | Name: Quinacillin disodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Quinacillin is semisynthetic penicillase-resistant penicillin for the treatment of bacterial infection.

Chemical Structure

Quinacillin disodium

CAS#985-32-0 (disodium)

Theoretical Analysis

MedKoo Cat#: 125303

Name: Quinacillin disodium

CAS#: 985-32-0 (disodium)

Chemical Formula: C18H14N4Na2O6S

Exact Mass: 460.0400

Molecular Weight: 460.37

Elemental Analysis: C, 46.96; H, 3.07; N, 12.17; Na, 9.99; O, 20.85; S, 6.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

1596-63-0 (free base) 985-32-0 (disodium)

Synonym

Quinacillin sodium; Disodium quinacillin; quinacillin disodium; K8064V0P9V; 985-32-0

IUPAC/Chemical Name

sodium (2S,5R,6R)-6-(3-carboxylatoquinoxaline-2-carboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

InChi Key

WFAXHOKRRRZBNN-HWROMZCQSA-L

InChi Code

InChI=1S/C18H16N4O6S.2Na/c1-18(2)12(17(27)28)22-14(24)11(15(22)29-18)21-13(23)9-10(16(25)26)20-8-6-4-3-5-7(8)19-9;;/h3-6,11-12,15H,1-2H3,(H,21,23)(H,25,26)(H,27,28);;/q;2*+1/p-2/t11-,12+,15-;;/m1../s1

SMILES Code

[Na+].[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C3=NC4=CC=CC=C4N=C3C([O-])=O)C([O-])=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 460.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Christie AB, Mitchell AA, Walker RS. Quinacillin. A study of a new penicillin. Scott Med J. 1966 May;11(5):176-81. doi: 10.1177/003693306601100505. PMID: 5941626. 2: SMITH JT, HAMILTON-MILLER JM, KNOX R. QUINACILLIN: A COMPARISON WITH OTHER PENICILLINASE-RESISTANT PENICILLINS. Nature. 1964 Sep 12;203:1148-50. doi: 10.1038/2031148a0. PMID: 14213664. 3: RICHARDS HC, HOUSLEY JR, SPOONER DF. QUINACILLIN: A NEW PENICILLIN WITH UNUSUAL PROPERTIES. Nature. 1963 Jul 27;199:354-6. doi: 10.1038/199354a0. PMID: 14058567. 4: Persaud KC, Pain RH, Virden R. Reversible deactivation of beta-lactamase by quinacillin. Extent of the conformational change in the isolated transitory complex. Biochem J. 1986 Aug 1;237(3):723-30. doi: 10.1042/bj2370723. PMID: 3492197; PMCID: PMC1147050.