p-Fluorofentanyl HCl | CAS#117332-92-0 | mu-opioid agonist | analog of fentanyl

MedKoo Cat#: 125270 | Name: p-Fluorofentanyl HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Parafluorofentanyl is a selective mu-opioid agonist and an analog of fentanyl.

Chemical Structure

p-Fluorofentanyl HCl

CAS#117332-92-0 (HCl)

Theoretical Analysis

MedKoo Cat#: 125270

Name: p-Fluorofentanyl HCl

CAS#: 117332-92-0 (HCl)

Chemical Formula: C22H28ClFN2O

Exact Mass: 390.1900

Molecular Weight: 390.93

Elemental Analysis: C, 67.59; H, 7.22; Cl, 9.07; F, 4.86; N, 7.17; O, 4.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

117332-92-0 (HCl) 90736-23-5 (free base)

Synonym

p-Fluorofentanyl hydrochloride; 117332-92-0; VP0NU00C3G; Para-fluorofentanyl hydrochloride; para-Fluorofentanyl (hydrochloride)

IUPAC/Chemical Name

N-(4-fluorophenyl)-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide;hydrochloride

InChi Key

CTXOPDVNXMUJCV-UHFFFAOYSA-N

InChi Code

InChI=1S/C22H27FN2O.ClH/c1-2-22(26)25(20-10-8-19(23)9-11-20)21-13-16-24(17-14-21)15-12-18-6-4-3-5-7-18;/h3-11,21H,2,12-17H2,1H3;1H

SMILES Code

CCC(N(C1=CC=C(F)C=C1)C2CCN(CCC3=CC=CC=C3)CC2)=O.[H]Cl

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 390.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ulens C, Van Boven M, Daenens P, Tytgat J. Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in mu-opioid receptor selectivity. J Pharmacol Exp Ther. 2000 Sep;294(3):1024-33. PMID: 10945855. 2: de Boer D, Goemans WP, Ghezavat VR, van Ooijen RD, Maes RA. Seizure of illicitly produced para-fluorofentanyl: quantitative analysis of the content of capsules and tablets. J Pharm Biomed Anal. 2003 Mar 10;31(3):557-62. doi: 10.1016/s0731-7085(02)00684-2. PMID: 12615244. 3: Lipiński PFJ, Szűcs E, Jarończyk M, Kosson P, Benyhe S, Misicka A, Dobrowolski JC, Sadlej J. Affinity of fentanyl and its derivatives for the σ₁-receptor. Medchemcomm. 2019 Jun 13;10(7):1187-1191. doi: 10.1039/c9md00222g. PMID: 31391893; PMCID: PMC6657672. 4: Trecki J, Gerona RR, Ellison R, Thomas C, Mileusnic-Polchan D. Notes from the Field: Increased Incidence of Fentanyl-Related Deaths Involving Para- fluorofentanyl or Metonitazene - Knox County, Tennessee, November 2020-August 2021. MMWR Morb Mortal Wkly Rep. 2022 Jan 28;71(4):153-155. doi: 10.15585/mmwr.mm7104a3. PMID: 35085219; PMCID: PMC9351528. 5: Ruangyuttikarn W, Law MY, Rollins DE, Moody DE. Detection of fentanyl and its analogs by enzyme-linked immunosorbent assay. J Anal Toxicol. 1990 May- Jun;14(3):160-4. doi: 10.1093/jat/14.3.160. PMID: 2374405.