GJN75561 | VMAT2 imaging agent | CAS#2253775-56-1

MedKoo Cat#: 124883 | Name: GJN75561

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GJN75561 is also named as FLORBENAZINE, (FLUOROPROPOXY, F-18, D6)-. It is a VMAT2 imaging agent.

Chemical Structure

GJN75561

CAS#2253775-56-1

Theoretical Analysis

MedKoo Cat#: 124883

Name: GJN75561

CAS#: 2253775-56-1

Chemical Formula: C21H26D618FNO3

Exact Mass: 370.2800

Molecular Weight: 370.53

Elemental Analysis: C, 68.07; H, 10.33; F, 4.86; N, 3.78; O, 12.95

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

(18F)D6-FP-(+)-DTBZ; FLORBENAZINE, (FLUOROPROPOXY, F-18, D6)-; GJN75561; GJN 75561; GJN-75561

IUPAC/Chemical Name

(2R,3R,11bR)-9-(3-(fluoro-18F)propoxy-1,1,2,2,3,3-d6)-3-isobutyl-10-methoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol

InChi Key

GNKGXQHHUUEYQV-JGIPMPBJSA-N

InChi Code

InChI=1S/C21H32FNO3/c1-14(2)9-16-13-23-7-5-15-10-21(26-8-4-6-22)20(25-3)11-17(15)18(23)12-19(16)24/h10-11,14,16,18-19,24H,4-9,12-13H2,1-3H3/t16-,18-,19-/m1/s1/i4D2,6D2,8D2,22-1

SMILES Code

[H][C@]12C[C@@H](O)[C@H](CC(C)C)CN1CCC3=CC(OC([2H])([2H])C([2H])([2H])C([2H])([2H])[18F])=C(OC)C=C23

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 370.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Liu F, Choi SR, Zha Z, Ploessl K, Zhu L, Kung HF. Deuterated 18F-9-O-hexadeutero-3-fluoropropoxyl-(+)-dihydrotetrabenazine (D6-FP-(+)-DTBZ): A vesicular monoamine transporter 2 (VMAT2) imaging agent. Nucl Med Biol. 2018 Feb;57:42-49. doi: 10.1016/j.nucmedbio.2017.11.009. Epub 2017 Dec 6. PMID: 29306111.