MedKoo Cat#: 124745 | Name: Anticancer agent 118
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Anticancer agent 118, a N‑acylated ciprofloxacin derivative, has anti-bacterial and anticancer activities.

Chemical Structure

Anticancer agent 118
Anticancer agent 118
CAS#864443-43-6

Theoretical Analysis

MedKoo Cat#: 124745

Name: Anticancer agent 118

CAS#: 864443-43-6

Chemical Formula: C19H19ClFN3O4

Exact Mass: 407.1048

Molecular Weight: 407.83

Elemental Analysis: C, 55.96; H, 4.70; Cl, 8.69; F, 4.66; N, 10.30; O, 15.69

Price and Availability

Size Price Availability Quantity
100mg USD 750.00 2 Weeks
200mg USD 1,150.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,650.00 2 Weeks
2g USD 5,650.00 2 Weeks
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Related CAS #
No Data
Synonym
Anticancer agent 118; Anticancer agent-118; Anticancer agent118
IUPAC/Chemical Name
7-(4-(2-chloroacetyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
InChi Key
AGTFKGLDCMHYMV-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H19ClFN3O4/c20-9-17(25)23-5-3-22(4-6-23)16-8-15-12(7-14(16)21)18(26)13(19(27)28)10-24(15)11-1-2-11/h7-8,10-11H,1-6,9H2,(H,27,28)
SMILES Code
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCN(C(CCl)=O)CC4)=C3)C1=O)O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 407.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Struga M, Roszkowski P, Bielenica A, Otto-Ślusarczyk D, Stępień K, Stefańska J, Zabost A, Augustynowicz-Kopeć E, Koliński M, Kmiecik S, Myslovska A, Wrzosek M. N-Acylated Ciprofloxacin Derivatives: Synthesis and In Vitro Biological Evaluation as Antibacterial and Anticancer Agents. ACS Omega. 2023 May 18;8(21):18663-18684. doi: 10.1021/acsomega.3c00554. PMID: 37273589; PMCID: PMC10233829.