MedKoo Cat#: 124741 | Name: FY-21 TFA
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

FY-21 is a selective inhibitor of LSD1.

Chemical Structure

FY-21 TFA
FY-21 TFA
CAS#3049681-20-8 (TFA)

Theoretical Analysis

MedKoo Cat#: 124741

Name: FY-21 TFA

CAS#: 3049681-20-8 (TFA)

Chemical Formula: C17H15F3N2O6

Exact Mass: 400.0882

Molecular Weight: 400.31

Elemental Analysis: C, 51.01; H, 3.78; F, 14.24; N, 7.00; O, 23.98

Price and Availability

Size Price Availability Quantity
100mg USD 750.00 2 Weeks
200mg USD 1,150.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,650.00 2 Weeks
2g USD 5,650.00 2 Weeks
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Related CAS #
601463-20-1 (free base) 178461-92-2 (HCl) 3049681-20-8 (TFA);
Synonym
FY-21; F -21; FY21; FY-21 TFA;
IUPAC/Chemical Name
1-(4-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol 2,2,2-trifluoroacetate
InChi Key
TUBPMNKNZANWJC-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H14N2O4.C2HF3O2/c18-13-7-10-5-6-16-15(12(10)8-14(13)19)9-1-3-11(4-2-9)17(20)21;3-2(4,5)1(6)7/h1-4,7-8,15-16,18-19H,5-6H2;(H,6,7)
SMILES Code
OC1=C(C=C2C(NCCC2=C1)C3=CC=C(C=C3)[N+]([O-])=O)O.FC(C(O)=O)(F)F
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 400.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yang C, Fang Y, Hu Y, Tian T, Liao G. Discovery of new tetrahydroisoquinolines as potent and selective LSD1 inhibitors for the treatment of MLL-rearranged leukemia. Eur J Med Chem. 2023 Sep 5;257:115516. doi: 10.1016/j.ejmech.2023.115516. Epub 2023 May 25. PMID: 37257211. 2: Polancich S, Patrician P, Miltner R, Meese K, Armstrong A, Layton S, Vander Noot R, Poe T, Hall AG. Reducing hospital acquired pressure injury in a learning health center: Making the case for quality. Learn Health Syst. 2022 Dec 15;7(3):e10355. doi: 10.1002/lrh2.10355. PMID: 37448459; PMCID: PMC10336481.