Fosigotifator is a eukaryotic translation initiation factor 2B (eIF2B) activator. Fosigotifator directly activates eIF2B, which counters the effects of stress-related signaling pathways that inhibit protein synthesis by phosphorylating eIF2. Through this activation, Fosigotifator promotes the restoration of normal protein synthesis rates in stressed or dysregulated cells. Fosigotifator has shown promise for conditions such as vanishing.
MedKoo Cat#: 140220
Name: Fosigotifator free acid
CAS#: 2415715-84-1 (free acid)
Chemical Formula: C25H27Cl2F2N2O9P
Exact Mass: 638.0799
Molecular Weight: 639.37
Elemental Analysis: C, 46.96; H, 4.26; Cl, 11.09; F, 5.94; N, 4.38; O, 22.52; P, 4.84
The following data is based on the product molecular weight 639.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
