II559 is a NNMT inhibitor. II559 showed enhanced cellular inhibition, with a cellular IC50 value of approximately 150 nM. , II559 reduced the cell viability with a GI50 value of ∼10 μM and suppressed the migration of aggressive clear cell renal cancer cell carcinoma cell lines.
MedKoo Cat#: 124440
Name: II-559
CAS#: N/A
Chemical Formula: C24H23Cl2N5O4
Exact Mass: 515.1100
Molecular Weight: 516.38
Elemental Analysis: C, 55.82; H, 4.49; Cl, 13.73; N, 13.56; O, 12.39
The following data is based on the product molecular weight 516.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
