MedKoo Cat#: 124247 | Name: HDAC-IN-57
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

HDAC-IN-57 is an orally active inhibitor of histone deacetylases (HDAC).

Chemical Structure

HDAC-IN-57
HDAC-IN-57
CAS#2716217-79-5

Theoretical Analysis

MedKoo Cat#: 124247

Name: HDAC-IN-57

CAS#: 2716217-79-5

Chemical Formula: C21H19N3O4

Exact Mass: 377.1376

Molecular Weight: 377.40

Elemental Analysis: C, 66.83; H, 5.07; N, 11.13; O, 16.96

Price and Availability

Size Price Availability Quantity
200mg USD 1,450.00 2 Weeks
500mg USD 2,850.00 2 Weeks
1g USD 4,250.00 2 Weeks
2g USD 6,450.00 2 Weeks
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Related CAS #
No Data
Synonym
HDAC-IN-57; HDAC-IN57; HDACIN-57; HDACIN57; HDAC IN 57
IUPAC/Chemical Name
N-(4-(hydroxycarbamoyl)benzyl)-2-(4-methoxyphenyl)isonicotinamide
InChi Key
BOPYJZYHIIFOOS-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H19N3O4/c1-28-18-8-6-15(7-9-18)19-12-17(10-11-22-19)20(25)23-13-14-2-4-16(5-3-14)21(26)24-27/h2-12,27H,13H2,1H3,(H,23,25)(H,24,26)
SMILES Code
COC1=CC=C(C2=NC=CC(C(NCC3=CC=C(C(NO)=O)C=C3)=O)=C2)C=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 377.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Kim HJ, Bae SC. Histone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs. Am J Transl Res. 2011 Feb;3(2):166-79. Epub 2010 Dec 26. PMID: 21416059; PMCID: PMC3056563.