MedKoo Cat#: 462483 | Name: CZC-8004
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase.

Chemical Structure

CZC-8004
CZC-8004
CAS#916603-07-1

Theoretical Analysis

MedKoo Cat#: 462483

Name: CZC-8004

CAS#: 916603-07-1

Chemical Formula: C17H16FN5

Exact Mass: 309.1390

Molecular Weight: 309.35

Elemental Analysis: C, 66.01; H, 5.21; F, 6.14; N, 22.64

Price and Availability

Size Price Availability Quantity
100mg USD 450.00 2 Weeks
250mg USD 850.00 2 Weeks
1g USD 1,850.00 2 Weeks
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Related CAS #
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Synonym
CZC-8004; CZC8004; CZC 8004; Dianilinopyrimidine-01; Dianilinopyrimidine_01;
IUPAC/Chemical Name
N2-(4-(aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine
InChi Key
UKOHFWNBTUJMMN-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H16FN5/c18-15-11-20-17(22-14-8-6-12(10-19)7-9-14)23-16(15)21-13-4-2-1-3-5-13/h1-9,11H,10,19H2,(H2,20,21,22,23)
SMILES Code
NCC1=CC=C(NC2=NC=C(F)C(NC3=CC=CC=C3)=N2)C=C1
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 309.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Deane FM, Lin AJS, Hains PG, Pilgrim SL, Robinson PJ, McCluskey A. FD5180, a Novel Protein Kinase Affinity Probe, and the Effect of Bead Loading on Protein Kinase Identification. ACS Omega. 2017;2(7):3828-3838. doi:10.1021/acsomega.7b00020 2: Bantscheff M, Eberhard D, Abraham Y, et al. Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nat Biotechnol. 2007;25(9):1035-1044. doi:10.1038/nbt1328