MedKoo Cat#: 130455 | Name: SA7060

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SA7060 is a neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE) dual inhibitor, preventing (DOCA)-salt-induced hypertension and related organ damage.

Chemical Structure

SA7060
SA7060
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130455

Name: SA7060

CAS#: N/A

Chemical Formula: C25H34N2O6

Exact Mass: 458.2417

Molecular Weight: 458.56

Elemental Analysis: C, 65.48; H, 7.47; N, 6.11; O, 20.93

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
SA7060; SA 7060; SA-7060
IUPAC/Chemical Name
(S)-2-(3-((S)-3-butoxy-2-hydroxy-3-oxopropyl)-3-isobutylureido)-3-(naphthalen-2-yl)propanoic acid
InChi Key
BUMOZZPKRUULDJ-VXKWHMMOSA-N
InChi Code
InChI=1S/C25H34N2O6/c1-4-5-12-33-24(31)22(28)16-27(15-17(2)3)25(32)26-21(23(29)30)14-18-10-11-19-8-6-7-9-20(19)13-18/h6-11,13,17,21-22,28H,4-5,12,14-16H2,1-3H3,(H,26,32)(H,29,30)/t21-,22-/m0/s1
SMILES Code
O=C(O)[C@@H](NC(N(C[C@@H](C(OCCCC)=O)O)CC(C)C)=O)CC1=CC=C2C=CC=CC2=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 458.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Kuro T, Okahara A, Nose M, Ikuse T, Matsumura Y. Effects of SA7060, a novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme, on deoxycorticosterone acetate-salt-induced hypertension in rats. Biol Pharm Bull. 2000 Jul;23(7):820-5. doi: 10.1248/bpb.23.820. PMID: 10919359.