MedKoo Cat#: 130397 | Name: BocA1V2PF1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BocA1V2PF1, an inhibitor of the apoptosis protein (IAP)-recruiting ligand, is used in targeted protein degradation and development of SNIPERs (specific and non-genetic IAP-dependent protein erasers).

Chemical Structure

BocA1V2PF1
BocA1V2PF1
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130397

Name: BocA1V2PF1

CAS#: N/A

Chemical Formula: C30H44N4O7

Exact Mass: 572.3210

Molecular Weight: 572.70

Elemental Analysis: C, 62.92; H, 7.74; N, 9.78; O, 19.56

Price and Availability

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100mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
BocA1V2PF1
IUPAC/Chemical Name
((S)-2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)-2-cyclohexylacetyl)-L-prolyl-L-phenylalanine
InChi Key
HVORUACRMULJRJ-HCUBDLJJSA-N
InChi Code
InChI=1S/C30H44N4O7/c1-19(31-29(40)41-30(2,3)4)25(35)33-24(21-14-9-6-10-15-21)27(37)34-17-11-16-23(34)26(36)32-22(28(38)39)18-20-12-7-5-8-13-20/h5,7-8,12-13,19,21-24H,6,9-11,14-18H2,1-4H3,(H,31,40)(H,32,36)(H,33,35)(H,38,39)/t19-,22-,23-,24-/m0/s1
SMILES Code
O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H]2N(C([C@@H](NC([C@@H](NC(OC(C)(C)C)=O)C)=O)C3CCCCC3)=O)CCC2)=O
Appearance
Solid
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 572.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Naito M, Ohoka N, Shibata N. SNIPERs-Hijacking IAP activity to induce protein degradation. Drug Discov Today Technol. 2019 Apr;31:35-42. doi: 10.1016/j.ddtec.2018.12.002. Epub 2019 Jan 14. PMID: 31200857.