MedKoo Cat#: 130366 | Name: (S,R,S)-VL285 Phenol-PEG4-NH2 HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(S,R,S)-VL285 Phenol-PEG4-NH2 HCl, which consists of a (VHL)-recruiting ligand with an alternative exit vector from VH032 (901490), a PEG linker, and a pendant amine that reacts with the carboxylic acid on the target ligand, is vital in the synthesis of molecules for PROTAC research and targeted protein degradation.

Chemical Structure

(S,R,S)-VL285 Phenol-PEG4-NH2 HCl
(S,R,S)-VL285 Phenol-PEG4-NH2 HCl
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130366

Name: (S,R,S)-VL285 Phenol-PEG4-NH2 HCl

CAS#: N/A

Chemical Formula: C39H54ClN5O9S

Exact Mass:

Molecular Weight: 804.40

Elemental Analysis: C, 58.23; H, 6.77; Cl, 4.41; N, 8.71; O, 17.90; S, 3.99

Price and Availability

Size Price Availability Quantity
50mg USD 730.00 2 Weeks
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Related CAS #
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Synonym
(S,R,S)-VL285 Phenol-PEG4-NH2 hydrochloride
IUPAC/Chemical Name
(2S,4R)-N-(2-((14-amino-3,6,9,12-tetraoxatetradecyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)pyrrolidine-2-carboxamide hydrochloride
InChi Key
WAOFVRRJKKKFIU-GJMJWEODSA-N
InChi Code
InChI=1S/C39H53N5O9S.ClH/c1-26(2)35(44-23-30-6-4-5-7-32(30)38(44)47)39(48)43-24-31(45)21-33(43)37(46)41-22-29-9-8-28(36-27(3)42-25-54-36)20-34(29)53-19-18-52-17-16-51-15-14-50-13-12-49-11-10-40;/h4-9,20,25-26,31,33,35,45H,10-19,21-24,40H2,1-3H3,(H,41,46);1H/t31-,33+,35+;/m1./s1
SMILES Code
O=C([C@H]1N(C([C@@H](N(CC2=C3C=CC=C2)C3=O)C(C)C)=O)C[C@H](O)C1)NCC4=CC=C(C5=C(C)N=CS5)C=C4OCCOCCOCCOCCOCCN.[H]Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 804.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL