Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity.
MedKoo Cat#: 127685
Name: Rolapitant hydrochloride hydrate
CAS#: 914462-92-3 (HCl hydrate)
Chemical Formula: C25H29ClF6N2O3
Exact Mass: 554.1771
Molecular Weight: 554.96
Elemental Analysis: C, 54.11; H, 5.27; Cl, 6.39; F, 20.54; N, 5.05; O, 8.65
The following data is based on the product molecular weight 554.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
