KB05, also known as N-(4-Bromophenyl)-N-phenylacrylamide, is a ‘Scout’ fragment and was found to display broad cysteine reactivity in the human proteome, being able to capture reactive cysteine residues of the E3 ubiquitin ligase pool, providing a tool for ligand discovery and for use in PROTAC development.
MedKoo Cat#: 130338
Name: KB05
CAS#: 1956368-15-2
Chemical Formula: C15H12BrNO
Exact Mass: 301.0102
Molecular Weight: 302.17
Elemental Analysis: C, 59.62; H, 4.00; Br, 26.44; N, 4.64; O, 5.29
The following data is based on the product molecular weight 302.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
