MedKoo Cat#: 130327 | Name: 3-(Boc-amino)propyl bromide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

3-(Boc-amino)propyl bromide is an agent used for alkylation for the synthesis of benzydamine analogs for soluble guanylate cyclase activation, an MDM2 inhibitor, and as a means of quaternization.

Chemical Structure

3-(Boc-amino)propyl bromide
3-(Boc-amino)propyl bromide
CAS# 83948-53-2

Theoretical Analysis

MedKoo Cat#: 130327

Name: 3-(Boc-amino)propyl bromide

CAS#: 83948-53-2

Chemical Formula: C8H16BrNO2

Exact Mass: 237.0364

Molecular Weight: 238.13

Elemental Analysis: C, 40.35; H, 6.77; Br, 33.56; N, 5.88; O, 13.44

Price and Availability

Size Price Availability Quantity
5g USD 350.00 2 Weeks
25g USD 550.00 2 Weeks
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Related CAS #
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Synonym
3-(Boc-amino)propyl bromide; tert-Butyl N-(3-bromopropyl)carbamate
IUPAC/Chemical Name
tert-butyl (3-bromopropyl)carbamate
InChi Key
IOKGWQZQCNXXLD-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H16BrNO2/c1-8(2,3)12-7(11)10-6-4-5-9/h4-6H2,1-3H3,(H,10,11)
SMILES Code
O=C(NCCCBr)OC(C)(C)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 238.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Selwood DL, Brummell DG, Budworth J, Burtin GE, Campbell RO, Chana SS, Charles IG, Fernandez PA, Glen RC, Goggin MC, Hobbs AJ, Kling MR, Liu Q, Madge DJ, Meillerais S, Powell KL, Reynolds K, Spacey GD, Stables JN, Tatlock MA, Wheeler KA, Wishart G, Woo CK. Synthesis and biological evaluation of novel pyrazoles and indazoles as activators of the nitric oxide receptor, soluble guanylate cyclase. J Med Chem. 2001 Jan 4;44(1):78-93. doi: 10.1021/jm001034k. PMID: 11141091. 2. Procopiou PA, Ford AJ, Gore PM, Hancock AP, Hodgson ST, Holmes DS, Looker BE, Vile S, Clark KL, Saunders KA, Slack RJ, Watts CJ. Identification of selective 8-(piperidin-4-yloxy)quinoline sulfone and sulfonamide histamine H1 receptor antagonists for use in allergic rhinitis. Bioorg Med Chem Lett. 2017 Nov 1;27(21):4914-4919. doi: 10.1016/j.bmcl.2017.09.020. Epub 2017 Sep 9. PMID: 28958623. 3. Beck HP, DeGraffenreid M, Fox B, Allen JG, Rew Y, Schneider S, Saiki AY, Yu D, Oliner JD, Salyers K, Ye Q, Olson S. Improvement of the synthesis and pharmacokinetic properties of chromenotriazolopyrimidine MDM2-p53 protein-protein inhibitors. Bioorg Med Chem Lett. 2011 May 1;21(9):2752-5. doi: 10.1016/j.bmcl.2010.11.027. Epub 2010 Nov 10. PMID: 21123063. 4. Venkataraman S, Zhang Y, Liu L, Yang YY. Design, syntheses and evaluation of hemocompatible pegylated-antimicrobial polymers with well-controlled molecular structures. Biomaterials. 2010 Mar;31(7):1751-6. doi: 10.1016/j.biomaterials.2009.11.030. Epub 2009 Dec 8. PMID: 20004014.