MedKoo Cat#: 555715 | Name: ARC39
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ARC39 is acid sphingomyelinase inhibitor (IC50 =20 nM).

Chemical Structure

ARC39
ARC39
CAS#15049-89-5 (free acid)

Theoretical Analysis

MedKoo Cat#: 555715

Name: ARC39

CAS#: 15049-89-5 (free acid)

Chemical Formula: C8H21NO6P2

Exact Mass: 289.0844

Molecular Weight: 289.20

Elemental Analysis: C, 33.22; H, 7.32; N, 4.84; O, 33.19; P, 21.42

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 Ready to ship
10mg USD 550.00 Ready to ship
25mg USD 950.00 Ready to ship
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Related CAS #
Synonym
ARC39; ARC-39; ARC 39;
IUPAC/Chemical Name
(1-aminooctane-1,1-diyl)bis(phosphonic acid)
InChi Key
BQIYVTCUMQVDEJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H21NO6P2/c1-2-3-4-5-6-7-8(9,16(10,11)12)17(13,14)15/h2-7,9H2,1H3,(H2,10,11,12)(H2,13,14,15)
SMILES Code
CCCCCCCC(P(O)(O)=O)(P(O)(O)=O)N
Appearance
To be determined
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 289.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: McVey MJ, Kim M, Tabuchi A, Srbely V, Japtok L, Arenz C, Rotstein O, Kleuser B, Semple JW, Kuebler WM. Acid sphingomyelinase mediates murine acute lung injury following transfusion of aged platelets. Am J Physiol Lung Cell Mol Physiol. 2017 May 1;312(5):L625-L637. doi: 10.1152/ajplung.00317.2016. Epub 2017 Mar 10. PubMed PMID: 28283474.