KS40008 is an inhibitor of the dual-specificity tyrosine phosphorylation-regulated kinase family (DYRK), specifically 1A/B, promoting anti-proliferative activity in colorectal cell lines. KS40008 has been found to promote mitochondrial dysfunction and endoplasmic reticulum stress, leading to the autophagic death of cancer cells.
MedKoo Cat#: 130316
Name: KS40008
CAS#: N/A
Chemical Formula: C18H13N3O3
Exact Mass: 319.0957
Molecular Weight: 319.32
Elemental Analysis: C, 67.71; H, 4.10; N, 13.16; O, 15.03
The following data is based on the product molecular weight 319.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
