N-Phenylthiourea is a tyrosinase inhibitor and building block. It increases the susceptibility of SK-MEL-188 melanoma cells in melanogenesis-inducing conditions to γ-radiation-induced cytotoxicity when used at a concentration of 0.01 μM. N-Phenylthiourea has been used as a precursor in the synthesis of compounds with antibacterial and antifungal activities. It has also been used as a genetic marker for taste because only some people detect it as a bitter taste.
MedKoo Cat#: 462686
Name: N-Phenylthiourea
CAS#: 103-85-5
Chemical Formula: C7H8N2S
Exact Mass: 152.0408
Molecular Weight: 152.22
Elemental Analysis: C, 55.24; H, 5.30; N, 18.40; S, 21.06
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMF | 30.0 | 197.09 | |
| DMSO | 30.0 | 197.09 | |
| DMSO:PBS (pH 7.2) (1:3) | 0.3 | 1.64 |
The following data is based on the product molecular weight 152.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
