MedKoo Cat#: 130222 | Name: sBADA

Description:

WARNING: This product is for research use only, not for human or veterinary use.

sBADA is a FDAA probe (green fluorescent D-amino acid probe) that is used for labeling peptidoglycans in the cell wall of bacteria. sBADA demonstrated its utility for visualizing peptidoglycan synthesis in Gram-negative and Gram-positive bacterial species. The permeability of FDAAs toward the outer-membrane of Gram-negative organisms, pinpointing the probes available for effective labeling in these species. The fluorescent d-amino acids can serve as ideal PG probes to elucidate bacterial cell growth and division in high spatiotemporal resolution, or to simply label bacterial cell surfaces for a variety of other applications in diverse bacteria

Chemical Structure

sBADA
sBADA
CAS#2376838-11-6

Theoretical Analysis

MedKoo Cat#: 130222

Name: sBADA

CAS#: 2376838-11-6

Chemical Formula: C17H21BF2N4O6S

Exact Mass: 458.1243

Molecular Weight: 458.24

Elemental Analysis: C, 44.56; H, 4.62; B, 2.36; F, 8.29; N, 12.23; O, 20.95; S, 7.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
Synonym
sBADA
IUPAC/Chemical Name
(R)-2-amino-3-(3-(5,5-difluoro-7,9-dimethyl-2-sulfo-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)propanamido)propanoic acid
InChi Key
OLMGTLBVHKBMSH-GFCCVEGCSA-N
InChi Code
InChI=1S/C17H21BF2N4O6S/c1-9-5-10(2)23-14(9)6-11-7-15(31(28,29)30)13(24(11)18(23,19)20)3-4-16(25)22-8-12(21)17(26)27/h5-7,12H,3-4,8,21H2,1-2H3,(H,22,25)(H,26,27)(H,28,29,30)/t12-/m1/s1
SMILES Code
CC1=C2N(C(C)=C1)B(F)([N]3=C(C(S(O)(=O)=O)=CC3=C2)CCC(NC[C@H](C(O)=O)N)=O)F
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Fluorescent d-amino acids (FDAAs) enable efficient in situ labeling of peptidoglycan in diverse bacterial species. Conducted by enzymes involved in peptidoglycan biosynthesis, FDAA labeling allows specific probing of cell wall formation/remodeling activity, bacterial growth and cell morphology. Their broad application and high biocompatibility have made FDAAs an important and effective tool for studies of peptidoglycan synthesis and dynamics, which, in turn, has created a demand for the development of new FDAA probes

Preparing Stock Solutions

The following data is based on the product molecular weight 458.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Hsu YP, Rittichier J, Kuru E, Yablonowski J, Pasciak E, Tekkam S, Hall E, Murphy B, Lee TK, Garner EC, Huang KC, Brun YV, VanNieuwenhze MS. Full color palette of fluorescent d-amino acids for in situ labeling of bacterial cell walls. Chem Sci. 2017 Sep 1;8(9):6313-6321. doi: 10.1039/c7sc01800b. Epub 2017 Jul 7. PMID: 28989665; PMCID: PMC5628581.