MedKoo Cat#: 130126 | Name: JNJ-9350
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

JNJ-9350 is an inhibitor of SMOX ( IC50= 0.01 μM) with a negative control of JNJ-4545.

Chemical Structure

JNJ-9350
JNJ-9350
CAS#326923-09-5

Theoretical Analysis

MedKoo Cat#: 130126

Name: JNJ-9350

CAS#: 326923-09-5

Chemical Formula: C25H22N6O

Exact Mass: 422.1855

Molecular Weight: 422.49

Elemental Analysis: C, 71.07; H, 5.25; N, 19.89; O, 3.79

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 650.00 2 Weeks
10mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
JNJ-9350; JNJ9350; JNJ 9350
IUPAC/Chemical Name
N-(3-(1H-imidazol-1-yl)propyl)-5,7-diphenylpyrazolo[1,5-a]pyrimidine-2-carboxamide
InChi Key
RIGHCDSORZCRDE-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H22N6O/c32-25(27-12-7-14-30-15-13-26-18-30)22-17-24-28-21(19-8-3-1-4-9-19)16-23(31(24)29-22)20-10-5-2-6-11-20/h1-6,8-11,13,15-18H,7,12,14H2,(H,27,32)
SMILES Code
O=C(C1=NN2C(C3=CC=CC=C3)=CC(C4=CC=CC=C4)=NC2=C1)NCCCN5C=CN=C5
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
The activation of SMOX, a catabolic enzyme, leads to DNA damage and increased oxygen species. SMOX plays an important role in the development of several cancers, including colorectal, gastric, prostate, and hepatocellular carcinoma.

Preparing Stock Solutions

The following data is based on the product molecular weight 422.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/JNJ-9350 2. https://www.eubopen.org/sites/www.eubopen.org/files/chemical-probes/EUbOPEN_ProbeSheet_JNJ_9350_v1.pdf