UV blocker A33 | CAS#N/A | photoprotective agent

MedKoo Cat#: 130106 | Name: UV blocker A33

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UV blocker A33 is a photoprotective agent against skin photoageing caused by exposure to UV-B rays. A33 specifically, had significant protective effects at 10 μM and 25 μM against UV-B (10 mJ/cm2) -induced damage in HDFs, and at 25 μM was found to actively prevent collagen degradation and restore some of the UV-B induced damage.

Chemical Structure

UV blocker A33

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130106

Name: UV blocker A33

CAS#: N/A

Chemical Formula: C38H51FO5

Exact Mass: 606.3721

Molecular Weight: 606.82

Elemental Analysis: Chemical Formula: Exact Mass: Molecular Weight: Elemental Analysis: C, 75.21; H, 8.47; F, 3.13; O, 13.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

UV blocker A33

IUPAC/Chemical Name

(2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bR)-11-((E)-2-Fluoro-4-methoxybenzylidene)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid

InChi Key

PQYZELFDIFTGAC-DMDLLLTPSA-N

InChi Code

InChI=1S/C38H51FO5/c1-33(2)29-11-12-38(7)30(36(29,5)20-23(31(33)41)17-22-9-10-24(44-8)18-27(22)39)28(40)19-25-26-21-35(4,32(42)43)14-13-34(26,3)15-16-37(25,38)6/h9-10,17-19,26,29-31,41H,11-16,20-21H2,1-8H3,(H,42,43)/b23-17+/t26-,29-,30+,31-,34+,35-,36-,37+,38+/m0/s1

SMILES Code

O=C([C@](CC[C@]1(C)CC[C@@]2(C)[C@]3(C)CC[C@@]4([H])C(C)(C)[C@@H](O)/C(C[C@]4(C)[C@]35[H])=C/C6=CC=C(OC)C=C6F)(C)C[C@@]1([H])C2=CC5=O)O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 606.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Kumar A, Archo S, Singh CP, Naikoo SH, Singh B, Kaur S, Tasduq SA. Photoprotective effect of 18β-glycyrrhetinic acid derivatives against ultra violet (UV)-B-Induced skin aging. Bioorg Med Chem Lett. 2022 Nov 15;76:128984. doi: 10.1016/j.bmcl.2022.128984. Epub 2022 Sep 24. PMID: 36167293.