ZY12201 | CAS#unknown | TGR5 agonist

MedKoo Cat#: 465355 | Name: ZY12201

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZY12201 is a novel potent and orally bioavailable TGR5 agonist.

Chemical Structure

ZY12201

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465355

Name: ZY12201

CAS#: unknown

Chemical Formula: C31H31FN4O3S

Exact Mass: 558.2101

Molecular Weight: 558.67

Elemental Analysis: C, 66.65; H, 5.59; F, 3.40; N, 10.03; O, 8.59; S, 5.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ZY12201; ZY 12201; ZY-12201;

IUPAC/Chemical Name

2-((2-(4-(1H-imidazol-1-yl)phenoxy)ethyl)thio)-5-(2-(3,4-dimethoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole

InChi Key

ZRQBEFYILDBORB-UHFFFAOYSA-N

InChi Code

InChI=1S/C31H31FN4O3S/c1-31(2,22-5-14-27(37-3)28(19-22)38-4)29-20-34-30(36(29)25-8-6-23(32)7-9-25)40-18-17-39-26-12-10-24(11-13-26)35-16-15-33-21-35/h5-16,19-21H,17-18H2,1-4H3

SMILES Code

FC1=CC=C(N2C(C(C)(C3=CC=C(OC)C(OC)=C3)C)=CN=C2SCCOC4=CC=C(N5C=CN=C5)C=C4)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 558.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Sojitra C, Dholakia C, Sudhakar P, Singh KK, Agarwal S. Identification of degradation impurity of TGR5 receptor agonist-ZY12201 by LC-MS technique during force degradation study. SN Appl Sci. 2021;3(6):660. doi: 10.1007/s42452-021-04660-y. Epub 2021 May 25. PMID: 34056545; PMCID: PMC8144688.