MedKoo Cat#: 122222 | Name: DOTAP methylsulfate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DOTAP methylsulfate is a cationic derivative of trimethylammonium linked with two 18-carbon fatty acid tails with single alkene groups in each tail. 18:1 TAP is a cationic liposome-forming compound that may be used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells.

Chemical Structure

DOTAP methylsulfate
DOTAP methylsulfate
CAS#144189-73-1 (methylsulfate)

Theoretical Analysis

MedKoo Cat#: 122222

Name: DOTAP methylsulfate

CAS#: 144189-73-1 (methylsulfate)

Chemical Formula: C43H83NO8S

Exact Mass: 773.5839

Molecular Weight: 774.20

Elemental Analysis: C, 66.71; H, 10.81; N, 1.81; O, 16.53; S, 4.14

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
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Synonym
DOTAP; DOTAP methylsulfate; 1,2-DOTAP; DOTAP Methyl Sulfate; 18:1 TAP (DOTAP, MS Salt)
IUPAC/Chemical Name
N,N,N-trimethyl-2,3-bis(oleoyloxy)propan-1-aminium methyl sulfate
InChi Key
RSMRWWHFJMENJH-LQDDAWAPSA-M
InChi Code
InChI=1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;
SMILES Code
[O-]S(OC)(=O)=O.C[N+](C)(C)CC(OC(CCCCCCC/C=C\CCCCCCCC)=O)([H])COC(CCCCCCC/C=C\CCCCCCCC)=O
Appearance
To be determined
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 774.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL