(S, R, S)-AHPC-PEG2-NHS ester is a synthetic PROTAC linker that incorporates an E3 ligase ligand with a PEG linker to empower PROTAC medicine chemistry. NHS ester is reactive with amine moiety. The hydrophilic PEG spacer increases its aqueous solubility.
MedKoo Cat#: 122169
Name: (S, R, S)-AHPC-PEG2-NHS ester
CAS#: N/A
Chemical Formula: C34H45N5O10S
Exact Mass: 715.2887
Molecular Weight: 715.82
Elemental Analysis: C, 57.05; H, 6.34; N, 9.78; O, 22.35; S, 4.48
The following data is based on the product molecular weight 715.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
